Compound ID | 788

Update compound information

Sch 37644

Class: Macrolide

Agent Type: Semisynthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive
Mechanism of action: Protein synthesis inhibitor
Description: Semisynthetic derivative of erythromycin
Institute where first reported: Schering Corp. (Merck & Co., US)
Year first mentioned: 1987
Development status: Experimental
Reason dropped: Less active than erythromycin and antibiotic A-56268
Chemical structure(s):
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Molecular weight: 952.13
Iso. SMILES: CCC1C(/C=C(/C=C\C(=O)C(CC(C(C(C(CC(=O)O1)OC(=O)C)C)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)OC(=O)C(C)(C)C)(C)O)N(C)C)OC(=O)C)CC=O)C)\C)COC(=O)C
InChI Key: VMUBYQIHWUUVRJ-GGNBEDJHSA-N
Can. SMILES: CCC1C(/C=C(\C)/C=C\C(=O)C(C)CC(CC=O)C(C(C)C(CC(=O)O1)OC(=O)C)OC2C(C(C(C(C)O2)OC3CC(C)(C(C(C)O3)OC(=O)C(C)(C)C)O)N(C)C)OC(=O)C)COC(=O)C
InChI: InChI=1S/C49H77NO17/c1-16-37-35(25-59-31(7)52)21-26(2)17-18-36(55)27(3)22-34(19-20-51)42(28(4)38(62-32(8)53)23-39(56)64-37)66-46-44(63-33(9)54)41(50(14)15)43(29(5)61-46)65-40-24-49(13,58)45(30(6)60-40)67-47(57)48(10,11)12/h17-18,20-21,27-30,34-35,37-38,40-46,58H,16,19,22-25H2,1-15H3/b18-17-,26-21+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/6443961
Citation: https://doi.org/10.7164/antibiotics.43.1131

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