Compound ID | 797
Anti-acpP peptide PNA
Class: Membrane-active agent
| Agent Type: | Synthetic; Direct acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Membrane-active agent. Blocks expression of the acpP gene through an antisense mechanism |
| Target Pathogen: | Active against Escherichia coli |
| Description: | A membrane-penetrating peptide carrying a phosphorodiamidate morpholino oligomer (PMO; an antisense oligomer); antisense peptide nucleic acid (PNA) |
| Institute where first reported: | AVIBioPharm. Inc. (Sarepta Therapeutics) |
| Year first mentioned: | 2004 |
| Development status: | Experimental |
| External links: | |
| Citations: |
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