Compound ID | 811

Update compound information

PF-00422602

Class: Oxazolidinone

Spectrum of activity: Gram-positive
Details of activity: Protein synthesis inhibitor; Effective against MRSA, VRE and PRSP
Institute where first reported: Pfizer, US; Durata (Actavis, USA)
Year first mentioned: 2006
Highest developmental phase: Preclinical
Development status: Inactive
Reason Dropped: No development has been reported and has been in pre-clinical trials since 2006 indicating discontinuation
Chemical structure(s):
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Molecular weight: 340.37
Iso. SMILES: C1CS(=O)CCC1C2=C(C=C(C=C2)N3C[C@@H](OC3=O)C(=O)N)F
InChI Key: BHMSJQPFCDTTCI-NYGWOBCZSA-N
Can. SMILES: C1=C(C=C(C(=C1)C2CCS(=O)CC2)F)N3C[C@H](C(=O)N)OC3=O
InChI: InChI=1S/C15H17FN2O4S/c16-12-7-10(18-8-13(14(17)19)22-15(18)20)1-2-11(12)9-3-5-23(21)6-4-9/h1-2,7,9,13H,3-6,8H2,(H2,17,19)/t9?,13-,23?/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/23729988
Citations:
  • https://pubmed.ncbi.nlm.nih.gov/17988109/

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