Compound ID | 812

PF-987296

Class: Oxazolidinone

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive
Mechanism of action: Protein synthesis inhibitor
Target Pathogen: Active against methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and penicillin-resistant Streptococcus pneumoniae
Description: Harris C, Barbachyn MR, Vara Prasad JVN, et al. Identification of a new trifluorophenyl oxazolidinone, PF-987296. 46th-Intersci-Conf-Antimicrobial-Agents-Chemother 2006;213
Institute where first reported: Pfizer, US; Durata (Actavis, USA)
Year first mentioned: 2006
Highest development stage: Preclinical
Development status: Experimental
Reason dropped: Has been in preclinical trials since 2006
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