Compound ID | 884

Update compound information

SEP 155342

Class: Quinoline-indole

Spectrum of activity: Gram-negative
Details of activity: Lysis followed bacteria death, thought to be related to membrane damage
Institute where first reported: Sepracor (Sunovion Pharmaceuticals, Inc)
Year first mentioned: 2000
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
Click here for structure editor
Molecular weight: 550.48
Iso. SMILES: ClC1=CC2=C(C=C1)NC=C2C3=NC4=CC(Cl)=C(C#CCN5CCCCC5)C=C4C(C(NCC(CN)O)=O)=C3
InChI Key: FRBLIFKXJAMUCN-UHFFFAOYSA-N
Can. SMILES: C1CCN(CC1)CC#CC2=CC3=C(C=C2Cl)N=C(C=C3C(=O)NCC(CN)O)C4=CNC5=C4C=C(C=C5)Cl
InChI: InChI=1S/C29H29Cl2N5O2/c30-19-6-7-26-22(12-19)24(17-33-26)27-13-23(29(38)34-16-20(37)15-32)21-11-18(25(31)14-28(21)35-27)5-4-10-36-8-2-1-3-9-36/h6-7,11-14,17,20,33,37H,1-3,8-10,15-16,32H2,(H,34,38)
External links:
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC151732/
  • https://journals.asm.org/doi/full/10.1128/aac.47.2.458-466.2003?cited-by=yes&legid=aac%3B47%2F2%2F458

    • AntibioticDB is supported by GARDP.

    If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

    The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.