Compound ID | 890
CP111905-00
Class: Hygromycin A
| Spectrum of activity: | Gram-negative |
| Details of activity: | Inhibits bacterial ribosomal peptidyl transferase. Equally potent at eliminating bacterial infection (S. hyodysenteriae) in mice ceca as Hyg-A. |
| Description: | Kamicker BJ and Lemay MA. Evaluation of Hygromycin A and its analog, CP11905-00. against Serpulina hyodysenteriae and Pasteurella multocida in vitro and in three murine infectious disease models. 32nd-Intersci-Conf-Antimicrobial-Agents-Chemother 1992; 338. |
| Institute where first reported: | Pfizer, USA |
| Year first mentioned: | 1992 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| PubChem link: | https://pubchem.ncbi.nlm.nih.gov/compound/6433481 |
| Citation: | https://pubs.acs.org/doi/abs/10.1021/jo00084a053 |
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