Compound ID | 899
GSQ 5028
Class: Small molecule antibacterial agent
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | DNA synthesis inhibitor. Binds to DNA minor groove resulting in inhibition of DNA replication and DNA-dependent RNA transcription |
| Target Pathogen: | Active against staphylococci and enterococci |
| Institute where first reported: | Oscient Pharmaceuticals |
| Year first mentioned: | 2001 |
| Development status: | Experimental |
| Reason dropped: | HARPs were first developed on by Genesoft which eventually merged with Oscient, however Oscient went bankrupt in 2009 |
| External links: | |
| Citations: |
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