Compound ID | 919
CNH365.396
Class: Tricyclic dione ester
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Active against all Gram positives MRSA, Bacillus anthracis tested and M. catarrhalis but no other Gram negatives tested. This was presented at ICAAC in 2012; in 2013, Trius was taken over by Cubist and in 2015, Cubist was taken over by Merck. Merck does not seem to be researching this |
| Description: | Hensler M, Soubih E, Jang K, et al. CNH365.396, a novel marine-derived compound with potent activity against methicillin resistant Staphylococcus aureus(MRSA). 50th-ICAAC 2012. |
| Institute where first reported: | Trius Therapeutics (Merck & Co., USA) |
| Year first mentioned: | 2012 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| Citation: |
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