Compound ID | 934

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Bay Y3118

Class: Fluoroquinolone

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Gram positive cocci and gram negatives. Testing against Gram positives demonstrated comparable to 2-32 times higher activity than ofloxacin, ciprpfloxacin and sparfloxacin.
Description: Inoue M and Hasobe T. In vitro antibacterial activities of BAY y 3118, a new quinolone. 33rd-Intersci-Conf-Antimicrobial-Agents-Chemother 1993; 388.
Institute where first reported: Bayer AG, Germany
Year first mentioned: 1992
Highest developmental phase: Phase 2
Development status: Inactive
Reason Dropped: Highly phototoxic (1)
Chemical structure(s):
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Molecular weight: 442.31
Iso. SMILES: C1C[C@H]2CN(C[C@H]2NC1)C3=C(C=C4C(=C3Cl)N(C=C(C4=O)C(=O)O)C5CC5)F.Cl
InChI Key: IDCUHOXUSMHTOK-OEQYQXMYSA-N
Can. SMILES: C1C[C@H]2CN(C[C@H]2NC1)C3=C(C4=C(C=C3F)C(=O)C(=CN4C5CC5)C(=O)O)Cl.Cl
InChI: InChI=1S/C20H21ClFN3O3.ClH/c21-16-17-12(19(26)13(20(27)28)8-25(17)11-3-4-11)6-14(22)18(16)24-7-10-2-1-5-23-15(10)9-24;/h6,8,10-11,15,23H,1-5,7,9H2,(H,27,28);1H/t10-,15+;/m0./s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/119374
Citations:
  • http://jac.oxfordjournals.org/content/51/suppl_1/21.full.pdf

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