Compound ID | 937

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Difloxacin

Synonym(s): A 56619

Class: Fluoroquinolone

Spectrum of activity: Gram-positive  &  Gram-negative
Institute where first reported: Abbott Laboratories; AbbieVie
Highest developmental phase: Phase 2
Development status: Inactive
Reason Dropped: A number of frequent side effects: appetite disorders; CNS disorders; dizziness; drowsiness; headache; insomnia; nausea; vision disorders; vomiting
Chemical structure(s):
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Molecular weight: 399.39
Iso. SMILES: CN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F
InChI Key: NOCJXYPHIIZEHN-UHFFFAOYSA-N
Can. SMILES: CN1CCN(CC1)C2=CC3=C(C=C2F)C(=O)C(=CN3C4=CC=C(C=C4)F)C(=O)O
InChI: InChI=1S/C21H19F2N3O3/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14/h2-5,10-12H,6-9H2,1H3,(H,28,29)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/56206
Guide to Pharmacology: difloxacin
Citation: https://journals.asm.org/doi/10.1128/aac.28.4.514

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