Difloxacin

Synonym(s): A 56619

Class: Fluoroquinolone

Spectrum of activity:	Gram-positive  &  Gram-negative
Institute where first reported:	Abbott Laboratories; AbbieVie
Highest developmental phase:	Phase 2
Development status:	Inactive
Reason Dropped:	A number of frequent side effects: appetite disorders; CNS disorders; dizziness; drowsiness; headache; insomnia; nausea; vision disorders; vomiting

Chemical structure(s):
Canonical SMILES:	CN1CCN(CC1)C2=CC3=C(C=C2F)C(=O)C(=CN3C4=CC=C(C=C4)F)C(=O)O
Isomeric SMILES:	CN1CCN(CC1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F
InChI:	InChI=1S/C21H19F2N3O3/c1-24-6-8-25(9-7-24)19-11-18-15(10-17(19)23)20(27)16(21(28)29)12-26(18)14-4-2-13(22)3-5-14/h2-5,10-12H,6-9H2,1H3,(H,28,29)
InChI Key:	NOCJXYPHIIZEHN-UHFFFAOYSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/56206

External links:
Guide to Pharmacology:	difloxacin
Main Source:	https://journals.asm.org/doi/10.1128/aac.28.4.514