Vermisporin

Class: Xanthone

Spectrum of activity:	Gram-positive  &  Gram-negative
Details of activity:	Anti-tubercular
Institute where first reported:	Meiji Seika Kaisha (Meiji Seika Pharma., Japan)
Year first mentioned:	1990
Highest developmental phase:	Preclinical
Development status:	Inactive
Reason Dropped:	Possible bioavailbility issues but waiting on access to a paper

Chemical structure(s):
Canonical SMILES:	CC(C)[C@H]1C(=O)/C(=C(\[C@@H]2C(C=C[C@H]3C[C@@H](C)C[C@@H](C)[C@H]32)[C@@]4(C)[C@H](C)O4)/O)/C(=O)N1C
Isomeric SMILES:	C[C@H]1C[C@H]([C@@H]2[C@H](C1)C=CC([C@H]2/C(=C/3\C(=O)[C@@H](N(C3=O)C)C(C)C)/O)[C@]4([C@@H](O4)C)C)C
InChI:	InChI=1S/C25H37NO4/c1-12(2)21-23(28)20(24(29)26(21)7)22(27)19-17(25(6)15(5)30-25)9-8-16-11-13(3)10-14(4)18(16)19/h8-9,12-19,21,27H,10-11H2,1-7H3/b22-20-/t13-,14+,15-,16-,17?,18+,19+,21-,25+/m0/s1
InChI Key:	OBDFYDGODWWFEX-UDEGNFRISA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/54695539

External links:
Guide to Pharmacology:	vermisporin
Citations:	https://www.ncbi.nlm.nih.gov/pubmed/25462220 http://www.ncbi.nlm.nih.gov/pubmed/1425739