Sanfetrinem

Synonym(s): GV 104326

Class: Beta-lactam (tribactam)

Spectrum of activity:	Gram-positive  &  Gram-negative
Details of activity:	Not very active against MRSA though is active in MSSA. Additionally demonstrates strong antimicrobial activity against S. pneumoniae, E. coli and H. influenzae
Institute where first reported:	GSK, USA
Year first mentioned:	1992
Highest developmental phase:	Phase 2 (NCT05388448)
Development status:	Unknown (as of 2025)

Chemical structure(s):
Canonical SMILES:	C[C@H]([C@@H]1[C@H]2[C@H]3CCC[C@@H](C3=C(C(=O)O)N2C1=O)OC)O
Isomeric SMILES:	C[C@H]([C@@H]1[C@H]2[C@H]3CCC[C@@H](C3=C(N2C1=O)C(=O)O)OC)O
InChI:	InChI=1S/C14H19NO5/c1-6(16)9-11-7-4-3-5-8(20-2)10(7)12(14(18)19)15(11)13(9)17/h6-9,11,16H,3-5H2,1-2H3,(H,18,19)/t6-,7+,8+,9-,11-/m1/s1
InChI Key:	ICFDDEJRXZSWTA-KJFVXYAMSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/71452

External links:
Guide to Pharmacology:	sanfetrinem
Citations:	http://aac.asm.org/content/38/10/2362 http://aac.asm.org/content/42/7/1858.abstract