Compound ID | 952

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Sanfetrinem

Synonym(s): GV 104326

Class: Beta-lactam (tribactam)

Spectrum of activity: Gram-positive & Gram-negative
Details of activity: Not very active against MRSA though is active in MSSA. Additionally demonstrates strong antimicrobial activity against S. pneumoniae, E. coli and H. influenzae
Institute where first reported: GSK, USA
Year first mentioned: 1992
Highest developmental phase: Phase 2 (NCT05388448)
Development status: Unknown (as of 2025)
Chemical structure(s):
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Molecular weight: 281.3
Iso. SMILES: C[C@H]([C@@H]1[C@H]2[C@H]3CCC[C@@H](C3=C(N2C1=O)C(=O)O)OC)O
InChI Key: ICFDDEJRXZSWTA-KJFVXYAMSA-N
Can. SMILES: C[C@H]([C@@H]1[C@H]2[C@H]3CCC[C@@H](C3=C(C(=O)O)N2C1=O)OC)O
InChI: InChI=1S/C14H19NO5/c1-6(16)9-11-7-4-3-5-8(20-2)10(7)12(14(18)19)15(11)13(9)17/h6-9,11,16H,3-5H2,1-2H3,(H,18,19)/t6-,7+,8+,9-,11-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/71452
Guide to Pharmacology: sanfetrinem
Citations:
  • http://aac.asm.org/content/38/10/2362
  • http://aac.asm.org/content/42/7/1858.abstract

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