Compound ID | 953
SRI-011225
Class: Beta-lactam
| Agent Type: | Semisynthetic; Small molecule; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Unknown |
| Target Pathogen: | Active against pathogens causing community-acquired pneumoniae, Staphylococcus aureus, Bacillus anthracis, drug-resistant Streptococcus pneumoniae, Francisella tularensis, and Enterococcus faecalis |
| Propensity to select resistant mutants: | Resistance could not be induced in F. tularensis |
| Description: | Jong L, Mortelmans K, Green C, Hokama L, Tran T, Sahner D. F-1531 - SRI-011225, a First-in-Class Bactericidal Antimicrobial Active Against Drug-Resistant Pathogens. 52nd-ICAAC-2012 2012; abstr. F-1531 |
| Institute where first reported: | SRI International, USA |
| Year first mentioned: | 2012 |
| Highest development stage: | Preclinical |
| Development status: | Experimental |
| External links: |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.