Compound ID | 957
MC-207252
Class: Antibiotic adjuvant
| Details of activity: | Modify the expression and/or function of PBP2a. Lowered the MICs of the tested β-lactams (methicillin, nafcillin, oxacillin, cefazolin and imipenem) against MRSA. |
| Description: | Chamberland S, Blais J, et al. MC-207252 abolishes PBP 2a mediated β-lactam resistance in Staphylococci. 35th-Intersci-Conf-Antimicrobial-Agents-Chemother 1995; 138 |
| Institute where first reported: | Microcide Pharmaceuticals (Essential Therapeutics [Ceased]) |
| Year first mentioned: | 1995 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| Citation: |
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