Compound ID | 975
EXEG1706
Class: Small molecule antibacterial agent
| Agent Type: | Semisynthetic; Small molecule; |
| Spectrum of activity: | Gram-positive & Antimycobacterial |
| Mechanism of action: | Unknown |
| Target Pathogen: | Active against Staphylococcus aureus including methicillin- and quinolone-resistant strains |
| Description: | Toxicity levels in macrophages of LC50 of 400 mg/L; AV-Gay Y, Pick N, Goode RL, et al. EXEG1706: a novel antimicrobial agent against methicillin-resistant Staphylococcus aureus.43rd-ICAAC 2003;269 |
| Institute where first reported: | eXegenics (Opko Health, USA) |
| Year first mentioned: | 2003 |
| Development status: | Experimental |
| Reason dropped: | Possible toxicity or company finance issues |
| External links: | |
| Citation: | https://doi.org/10.1099/jmm.0.46319-0 |
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