Compound ID | 977
VRC 5264
| Spectrum of activity: | Gram-positive |
| Details of activity: | Enzyme inhibitors |
| Institute where first reported: | Veriscor (Pfizer, USA) |
| Year first mentioned: | 2002 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| Reason Dropped: | an early LpxC inhibitor; in geneal these have been subject to resistance by bypass mutation; also some tox. Many groups working on LpxC inhibitors - nothing with the right characteriztics yet.- (LS) |
| External links: | |
| Citation: |
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