Compound ID | 981

Update compound information

Leinamycin

Synonym(s): DC107

Class: Natural product antibiotic

Agent Type: Natural product; Small molecule; Direct acting;
Mechanism of action: DNA synthesis inhibitor. DNA alkylating
Institute where first reported: Tokyo Res. Labs and Pharm Labs
Year first mentioned: 1990
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 510.65
Iso. SMILES: C[C@@H]1C2=NC(=CS2)/C=C\C=C\C(=O)[C@@H](/C=C(/CC[C@@]3(CC(=O)N1)[C@@](C(=O)SS3=O)(C)O)\C)O
InChI Key: ZHTRILQJTPJGNK-FYBAATNNSA-N
Can. SMILES: C/C/1=C\[C@H](C(=O)/C=C/C=C\C2=CSC(=N2)[C@@H](C)NC(=O)C[C@]3(CC1)[C@](C)(C(=O)SS3=O)O)O
InChI: InChI=1S/C22H26N2O6S3/c1-13-8-9-22(21(3,29)20(28)32-33(22)30)11-18(27)23-14(2)19-24-15(12-31-19)6-4-5-7-16(25)17(26)10-13/h4-7,10,12,14,17,26,29H,8-9,11H2,1-3H3,(H,23,27)/b6-4-,7-5+,13-10+/t14-,17-,21+,22-,33?/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/9849230
Guide to Pharmacology: leinamycin
Citations:
  • https://doi.org/10.1073/pnas.1716245115
  • https://doi.org/10.7164/antibiotics.42.333

    • AntibioticDB is supported by GARDP.

    If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

    The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.