Compound ID | 986
N-methyl/ethyl-lincomycin stereochemical derivatives
Class: Lincosamide
| Spectrum of activity: | Gram-positive |
| Details of activity: | They bind to the 23s portion of the 50S subunit of bacterial ribosomes and cause premature dissociation of the peptidyl-tRNA from the ribosome |
| Institute where first reported: | Chemical Pharmacology department, Abbot Laboratories, North Chicago, Illinois |
| Year first mentioned: | 1965 |
| Highest development stage: | Preclinical |
| Development status: | Inactive |
| External links: | |
| Citation: | http://pubs.acs.org/doi/abs/10.1021/jm00294a005 |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.