Compound ID | 986

N-methyl/ethyl-lincomycin stereochemical derivatives

Class: Lincosamide

Spectrum of activity: Gram-positive
Details of activity: They bind to the 23s portion of the 50S subunit of bacterial ribosomes and cause premature dissociation of the peptidyl-tRNA from the ribosome
Institute where first reported: Chemical Pharmacology department, Abbot Laboratories, North Chicago, Illinois
Year first mentioned: 1965
Highest developmental phase: Preclinical
Development status: Inactive

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