AntibioticDB

LL-37, Cathelicidin

Antimicrobial peptide (cationic, human cathelicidin)

Saint Joseph University of Beirut, Microbiology Laboratory, School of Pharmacy, Beirut, Lebanon, Zayed University, College of Natural and Health Sciences, Dubai, United Arab Emirates, Institut Pasteur/Faculté de médecine Cochin, Unité de Mucoviscidose et Bronchopathies Chroniques

2013

Highest development stage: Preclinical
Development status: Active
Gram-positive activity
Gram-negative activity
Mechanism of Action/Target pathogen: Active against multidrug-resistant Staphylococcus aureus and Pseudomonas aeruginosa
GtoPDB link: https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=5527
Source: https://www.sciencedirect.com/science/article/pii/S000527360600126X
Citation (1): https://www.frontiersin.org/articles/10.3389/fimmu.2013.00143/full
Citation (2): https://www.escmid.org/escmid_publications/escmid_elibrary/?q=Cationic+antimicrobial+peptides%3A+alternatives+and%2For+adjuvants+to+antibiotics+active+against+multidrug-resistant+Staphylococcus+aureus+and+Pseudomonas+aeruginosa&id=2173&L=0&x=0&y=0
Compound/Drug Structure: https://pubchem.ncbi.nlm.nih.gov/compound/16198951