AntibioticDB

Epiroprim, Ro 11-8958

Diaminopyrimidine

1993

Development status: Inactive
Gram-positive activity
Mechanism of Action/Target pathogen: Inhibits dihydrofolic acid reductase and thus, the synthesis of purine. Active against Gram-positive bacteria including trimethoprim-resistant strains.
Additional information: Synthetic compound. Trimethoprim derivative
GtoPDB link: https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=12327
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC163334/
Citation (1): https://link.springer.com/article/10.1007/BF00931533
Compound/Drug Structure: https://pubchem.ncbi.nlm.nih.gov/compound/68916