Highest development stage: Phase 1

Development status: Inactive

Gram-positive activity

Mechanism of Action/Target pathogen: Binds to the peptidyl transferase component of the 50S subunit of ribosomes, thus inhibiting peptide bond formation and bacterial protein synthesis. It is active against Gram-positive bacteria.

Additional information: Semisynthetic macrolide, 6,11-bridged bicyclolide