Development status: Experimental

Gram-positive activity

Gram-negative activity

Mechanism of Action/Target pathogen: Active against methicillin-resistant <i>Staphylococcus aureus</i>, daptomycin-resistant <i>Staphylococcus aureus</i>, vancomycin-intermediate <i>Staphylococcus aureus</i>, vancomycin-resistant <i>Enterococcus</i>, and <i>Haemophilus influenzae S</i>J7; binds to pyrophosphate moiety of C55PP, lipid II, and lipid IIIWTA

Additional information: Natural product from 'uncultured' soil bacteria <i>Eleftheria terrae ssp. Carolina; </i>no cytotoxic activity towards NIH/3T3 and HepG2 mammalian cells at 100 mg/L (highest tested vs MIC at 0.125 to 2 mg/L)