AntibioticDB

BB2-50F

Antivirulence agent (bacterial flagellar motor inhibitor)

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia

2021

Development status: Experimental
Mechanism of Action/Target pathogen: Inhibits flagellar motility
Additional information: Synthetic compound derived from amiloride (a diuretic drug that inhibits bacterial motility)
GtoPDB link: https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=13072
Source: https://journals.asm.org/doi/pdf/10.1128/jb.00367-21
Compound/Drug Structure: https://pubchem.ncbi.nlm.nih.gov/compound/135393470