Highest development stage: Preclinical

Development status: Inactive

Gram-negative activity

Mechanism of Action/Target pathogen: Generally poor activity against Gram positive aerobes and anaerobes (1) Excellent activity against gram - organisms including Pseudomonas and Acinetobacter.

Reason dropped: Resistance issues (JS)

Additional information: Breuer, H., et al. "Structure-activity relationships among sulfonylaminocarbonyl activated monobactams leading to SQ-83,360." Program and Abstracts of the 25th Intersci. Conf. on Antimicrob. Agents Chemother. No. 371.